Category: Virology

Hepatitis B Virus- Structure, Epidemiology, Symptoms, Pathogenesis, Diagnosis, Treatment and Vaccines 4.65/5 (60)

Hepatitis B Virus- Structure, Epidemiology, Symptoms, Pathogenesis, Diagnosis, Treatment and Vaccines

Hepatitis B Virus- Structure, Epidemiology, Symptoms, Pathogenesis, Diagnosis, Treatment and Vaccines The hepatitis B virus is a DNA virus belonging to the Hepadnaviridae family causing hepatitis B in humans.  Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease. Group: Group VII (dsDNA-RT) Family: Hepadnaviridae Genus: Orthohepadnavirus Species: […]

Zika Virus- Structure, Genome, Symptoms, Transmission, Pathogenesis, Diagnosis 4.48/5 (189)

Zika-Virus--Structure,-Genome,-Symptoms,-Transmission,-Pathogenesis,-Diagnosis

Zika Virus- Structure, Genome, Symptoms, Transmission, Pathogenesis, Diagnosis Zika Virus (ZIKV) is mosquito-borne emerging flavivirus which was first identified in Zika Forest of Uganda in 1947 in rhesus monkeys. It was later identified in humans in 1968 for the first time in Nigeria. Different outbreaks of Zika virus disease have been recorded in Africa, the Americas, Asia and the […]

Differences Between Chickenpox and Smallpox 4.44/5 (48)

Differences Between Chickenpox and Smallpox

Differences Between Chickenpox and Smallpox S.N Characteristics Chickenpox Smallpox 1 Causative Agent Varicella Zoster Virus (Herpes Virus) Variola virus (Pox Virus) 2 Incubation period 14-21 days 7-17 days 3 Severity Chickenpox is less deadly comparing to small pox. Smallpox is deadly severe comparing to chicken pox. 4 Lesions Lesions first appear on the face or […]

Differences Between Antigenic Shift and Antigenic Drift 4.72/5 (123)

Antigenic Shift and Antigenic Drift

Differences Between Antigenic Shift and Antigenic Drift Influenza Virus are remarkable because of the frequent antigenic change that occurs in HA (hemagglutinin) or NA (neuraminidase). The two surface antigens of influenza undergo antigenic variation independent of each other. They are Antigenic Shift and Antigenic Drift. Some of the Differences Between Antigenic Shift and Antigenic Drift […]

Techniques of Virus Cultivation 4.43/5 (253)

Inoculation into embryonated egg

Techniques of Virus Cultivation Viruses are obligate intracellular parasites so they depend on host for their survival. They cannot be grown in non-living culture media or on agar plates alone, they must require living cells to support their replication. The primary purpose of virus cultivation is: To isolate and identify viruses in clinical samples. To […]

Replication of Ebola Virus 4.28/5 (25)

Replication of Ebola Virus

Replication of Ebola Virus Ebola Virus do not replicate through any kind of cell division; rather, they use a combination of host and virally encoded enzymes, alongside host cell structures, to produce multiple copies of viruses. These then self-assemble into viral macromolecular structures in the host cell. The virus completes a set of steps when infecting […]

Signs and Symptoms of Ebola Virus Disease 5/5 (2)

Signs and Symptoms of Ebola Virus Disease

Signs and Symptoms of Ebola Virus Disease Symptoms may appear anywhere from 2 to 21 days after exposure to Ebola, but the average is 8 to 10 days. Ebola Zaire kills people quickly, typically 7 to 14 days after symptoms appear. A person can have the virus but not show any symptoms for as long […]

Structure of Ebola Virus 4.56/5 (9)

Ebola Virus Structure

  Structure of Ebola Virus Ebola Virus are generally approximately 80 nm in diameter, 970 nm long. They are cylindrical/tubular, and contain viral envelope, matrix, and nucleocapsid components. The virus generally appears in a long, filamentous form, but it can also be “U-shaped,” in the shape of a “6” (the “shepherd’s crook” appearance), or even […]

Genome of Ebola Virus 4.33/5 (3)

Ebola Virus Genome

Genome of Ebola Virus Ebola Virus have a negative-sense, non-segmented single stranded linear RNA genome about 18-19 kb in size. The 3′ terminus is not polyadenylated and the 5′ end is not capped. It contains approximately 19,000 base pairs. It encodes seven structural proteins: nucleoprotein (NP), polymerase cofactor (VP35), (VP40), GP, transcription activator (VP30), VP24, […]

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